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Hypospadias

Hypospadias: Causes, Symptoms, Diagnosis, and Treatment

Hypospadias is a relatively common congenital condition in males, yet it often remains under-discussed. Understanding hypospadias, its causes, symptoms, diagnosis, and treatment options can help parents and patients make informed decisions about care, especially when considering specialized treatment options like those available in India through expert reconstructive urologists.

What is Hypospadias?

Hypospadias is a birth defect of the urethral tube that carries urine from the bladder to the outside of the body. In hypospadias, the urethral opening is not located at the usual tip of the penis. Instead, it can be found anywhere along the underside of the penis, scrotum, or even perineum.

The severity of hypospadias varies greatly, from minor displacement to significant anomalies involving both urinary and sexual functions.

In addition to the misplaced urethral opening, hypospadias may also involve:

  • Downward curvature of the penis (chordee)
  • Abnormal spraying of urine
  • Undeveloped foreskin

If untreated, hypospadias can impact urinary function, sexual function, and self-esteem later in life.

What are the Causes of Hypospadias?

Hypospadias develops in the fetus during early pregnancy due to incomplete development of the urethra. While the exact cause is unclear, several factors may contribute:

  • Genetic factors: A family history of hypospadias increases the risk. Mutations affecting hormone production or receptor sensitivity may play a role.
  • Hormonal influences: Disruptions in testosterone or androgen levels during pregnancy may interfere with urethral formation.
  • Environmental factors: Exposure to chemicals like pesticides or industrial pollutants may affect fetal development.
  • Maternal age and health: Advanced maternal age or certain fertility treatments may be associated with increased risk.

Signs and Symptoms

Signs of hypospadias are usually evident at birth. Common symptoms include:

  • Urethral opening located on the underside of the penis
  • Downward curvature of the penis (chordee)
  • Hooded appearance of the penis due to incomplete foreskin
  • Difficulty directing urine stream
  • Spraying or dribbling of urine

In severe cases, it can affect urination, erection, and even fertility if left untreated.

Diagnosis

Hypospadias is typically diagnosed at birth during a routine examination. Pediatricians or neonatologists can identify the abnormal urethral position and other features.

In more complex cases, imaging such as kidney and bladder ultrasound may be used to detect related urinary abnormalities.

Important: Circumcision should not be performed on infants with hypospadias, as the foreskin may be required for surgical repair.

Latest Treatment Options for Hypospadias

The main goal of treatment is to create a straight penis with a urethral opening at the tip. Modern surgical advancements have significantly improved outcomes, especially under expert care.

While non-surgical treatments are rare, innovations in surgery include:

  • Tissue engineering: Bioengineered tissues are being explored for urethral reconstruction.
  • Minimally invasive techniques: Some early-stage repairs are using endoscopic methods.
  • 3D surgical planning: Advanced imaging helps surgeons plan repairs more precisely.

Surgical repair remains the gold standard treatment for most cases.

Surgical Treatment

Hypospadias repair surgery (urethroplasty) usually involves:

  • Correction of penile curvature (chordee)
  • Reconstruction of the urethra to reach the penile tip
  • Cosmetic correction, including foreskin repair or circumcision

Surgical techniques vary by severity:

  • TIP Urethroplasty (Snodgrass Procedure): Commonly used for distal hypospadias.
  • Onlay Flap: Suitable for proximal or complex cases.
  • Two-stage Repair: Used in severe or redo cases.

Success rates are high when performed by experienced specialists, with minimal complications.

When is the Right Time for Surgery?

Most experts recommend surgery between 6 to 18 months of age. Early surgery benefits include:

  • Minimal psychological impact
  • Better healing and tissue response
  • Improved cosmetic and functional outcomes

However, surgery can also be successfully done in older children or adults, especially for untreated or failed cases.

Who Performs Hypospadias Surgery?

Hypospadias surgery should be done by a pediatric urologist or a reconstructive urologist with expertise in genital and urinary reconstruction. Complex cases require skilled handling to ensure long-term functionality and appearance.

Hypospadias in Kids

In children, early treatment helps prevent embarrassment, stigma, and complications. A child-friendly surgical approach and compassionate care ensure optimal recovery, both physically and emotionally.

Hypospadias in Adults

Adult cases typically involve:

  • Untreated childhood hypospadias
  • Failed previous surgeries

Challenges include scar tissue, poor skin quality, and higher complication risks. However, modern grafting techniques (e.g., buccal mucosa grafts) make successful outcomes possible under expert care.

Why Choose Reconstructive Urologists in India for Hypospadias Repair?

India is a global leader in complex urological procedures, offering several advantages:

  • Expert Surgeons: Highly trained in high-volume centers
  • Modern Infrastructure: Advanced tools like 3D imaging and microsurgery
  • Affordability: Lower treatment costs compared to Western nations
  • Integrated Care: Preoperative evaluation to postoperative support
  • Proven Success: High success rates in primary and redo surgeries
  • Personalized Treatment: Patient-centered approach with detailed counseling

Choosing a skilled Indian urologist ensures access to world-class care with high success and satisfaction rates.

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